Correlation between neuromelanin-sensitive MR imaging and 123I-FP-CIT SPECT in patients with parkinsonism
نویسندگان
چکیده
منابع مشابه
[123I]FP-CIT SPECT in atypical degenerative parkinsonism
Parkinson’s disease (PD) is the second most common neurodegenerative disorder [1], yet early accurate diagnosis remains challenging. The estimated prevalence of PD is 0.5–1% in those aged 65–69 years and 1–3% in those aged ≥80 years [1]. Although the clinical diagnosis of PD may be straightforward in cases with a classic presentation [2], accurate distinction between PD and atypical degenerativ...
متن کاملFocal 123I-FP-CIT SPECT Abnormality in Midbrain Vascular Parkinsonism
Cerebrovascular diseases are considered among possible causes of acute/subacute parkinsonism, representing up to 22% of secondary movement disorders. In cases of suspected vascular parkinsonism (VP), dopamine transporter SPECT has been highly recommended to exclude nigrostriatal dopaminergic degeneration. We report the case of a hemiparkinsonism related to a left midbrain infarct with focal lat...
متن کاملAccurate differentiation of parkinsonism and essential tremor using visual assessment of [123I]-FP-CIT SPECT imaging: the [123I]-FP-CIT study group.
OBJECTIVE To evaluate whether visual assessment of [123I]-FP-CIT (DaTSCAN, Nycomed Amersham, plc) single photon emission computerized tomography (SPECT) images can differentiate between parkinsonism and essential tremor (ET). METHODS [123I]-FP-CIT SPECT imaging was conducted in a six-center study of 158 patients with a clinical diagnosis of parkinsonism compared with 27 ET cases and 35 health...
متن کاملImaging of serotonin transporters with [123I]FP-CIT SPECT in the human hypothalamus
BACKGROUND Serotonergic neurons in the rodent hypothalamus are implicated in key neuroendocrine and metabolic functions, including circadian rhythmicity. However, the assessment of the serotonergic system in the human hypothalamus in vivo is difficult as delineation of the hypothalamus is cumbersome with conventional region-of-interest analysis. In the present study, we aimed to develop a metho...
متن کاملClinicopathological and 123I‐FP‐CIT SPECT correlations in patients with dementia
The relationship between clinicopathologic diagnosis and 123I-FP-CIT SPECT in 18 patients with dementia (12 with Lewy body disease) from one center in the United States was assessed. The sensitivity and specificity of abnormal 123I-FP-CIT SPECT with reduced striatal uptake on visual inspection for predicting Lewy body disease were 91.7% and 83.3%, respectively. The mean calculated putamen to oc...
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ژورنال
عنوان ژورنال: Neuroradiology
سال: 2016
ISSN: 0028-3940,1432-1920
DOI: 10.1007/s00234-016-1644-7